BOVACLOX DRY COW: ENHANCED ACTIVITY THROUGH A COMBINATION OF ACTIVES.
Bovaclox is an ideal and cost-effective Dry Cow Therapy (DCT) for low challenge situations.

With Bovaclox Dry Cow you have:

  • Enhanced activity through a combination of actives
  • A short-acting DCT option
  • Cover for the important period of involution when cows are highly prone to new intramammary infections
  • Cost-effective, broad-spectrum mastitis control.

Bovaclox has a minimum treatment to calving interval of 30 days. A reduction in new infections in the late dry period is not achieved using short-acting DCT.

Bovaclox is a broad-spectrum combination of cloxacillin and ampicillin, effective against important mastitis pathogens.

Cloxacillin is a semi-synthetic penicillin, utilised to target penicillinase producing Staphylococci. Cloxacillin is less potent than penicillin vs non-penicillinase producing Gram-positive bacteria17 and has no appreciable Gram-negative activity.

Dual activity enhances effectiveness.

The addition of ampicillin confers several advantages:

  • An additive (and in some cases synergistic) action
  • An extension of spectrum
  • Gram-negative pathogens (notably coliforms)
  • Higher potency against Streptococci.

This is especially important in light of reports of oxacillin/cloxacillin resistance in Streptococcal isolates from New Zealand mastitis cases.18

Bovaclox maintains effective levels of antibiotic in udder tissue and secretions to prevent new infections for up to four weeks, including those caused by:

  • S. aureus and coagulase negative staph. (including penicillin-resistant strains)
  • Streptococci: S. uberis, S. dysgalactiae, S. agalactiae
  • Acarnobacterium (Actinomyces) species
  • Coliform bacteria at dry off.
17
Van Os et al. (1976). Comparative in vitro studies of a number of anti-mastitis antibiotics. Tijdschrift voor Diergeneeskunde.
18
Gibson (2007). Oxacillin resistance in Streptococcus uberis. NZ Veterinary Pathology ‘Synopse’ issue 25.
19
McDougall, S. et al. (2014). Antimicrobial resistance in Staphylococcus aureus, Streptococcus uberis and Streptococcus dysgalactiae from dairy cows with mastitis. NZVJ. 62(2):68-76.